The Embden- Meyerhof pathway or as we all call it, glycolysis, is the pathway for acquiring energy from carbohydrates. It is a ten step process and each step is enzyme catalyzed resulting in the production of energy in the form of ATP and NADH (Pratt, 2012).
- It begins with glucose, a carbohydrate consisting of mainly six carbons.
- The carb is oxidized and two (3-carbon) pyruvate.
- Each metabolized molecule produces two ATP and two NADH molecules.
- Glycolysis interacts with other pathways of metabolic reactions.
- During the pathway, other molecules (like glucose-6-phosphate) come in at the 2nd step.(Stoker, 2010)
Three parts, ten steps, and no this isn’t a dance move :|. Glycolysis is as complicated as it is tear-inducing (well… for those who’ll have to memorize it, anyway).
A few facts:
- Glycolysis can occur in anaerobic and aerobic conditions.
- It’s the oldest metabolic pathway known to man.
- Abnormally high rates may lead to tumor cell formation (the Warburg effect).
- Glycolysis is occurs everywhere in the body.
- It’s responsible for the process of fermentation where yeast is converted into alcohol.
With finals right around the corner… the truth is…
Christ, Ethan J. “Columbia University Academic Commons.” 2009. http://academiccommons.columbia.edu/item/ac:129890 (accessed March 8, 2014).
Glycolysis.org. Glycolysis.org. February 15, 2012. http://www.glycolysis.org/things-to-know-about-glycolysis.html (accessed March 8, 2014).
Pratt, Charlotte W. Essential Biochemistry. December 20, 2012. http://www.wiley.com/college/pratt/0471393878/instructor/structure/glycolysis/index.html (accessed March 8, 2014).
Stoker, H. Stephen. General, Organic and Biological Chemistry. Belmont: Brooks/Cole, Cengage Learning, 2010.
Contributors: Christine, Roi (Editor)